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Article

NADPH oxidase activity selectively modulates vascular endothelial growth factor signaling pathways.

The Journal of biological chemistry - 30 Nov 2007

Abid Md Ruhul, Spokes Katherine C, Shih Shou-Ching, Aird William C

Abstract excerpt

Vascular endothelial growth factor (VEGF) and reactive oxygen species (ROS) play critical roles in vascular physiology and pathophysiology. We have demonstrated previously that NADPH oxidase-derived ROS are required for VEGF-mediated migration and proliferation of endothelial cells. The goal of this study was to determine the extent to which VEGF signaling is coupled to NADPH oxidase activity. Human umbilical...

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PMID: 17908694
DOI: 10.1074/jbc.M702175200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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