Article
The role of endogenous NADPH oxidases in airway and pulmonary vascular smooth muscle function.
Antioxidants & redox signaling - 1 Dec 2003
Hoidal John R, Brar S S, Sturrock Anne B, Sanders Karl A, Dinger Bruce, Fidone Salvador, Kennedy Thomas P
Abstract excerpt
Reactive oxygen species generated from NADPH oxidase(s) in airway smooth muscle cells and pulmonary artery smooth muscle cells are important signaling intermediates. Nox4 appears to be the predominant gp91 homologue in these cells. However, expression of NADPH oxidase components is dependent on phenotype, and different homologues may be expressed during different functional states of the cell. NADPH oxidase(s)...
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