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Regulation of cardiovascular diseases by histone deacetylases and NADPH oxidases

4 Oct 2024

Abstract excerpt

Histone deacetylases (HDACs) play critical roles in cardiovascular diseases (CVDs). In addition, reactive oxygen species (ROS) produced by NADPH oxidases (NOXs) exert damaging effects due to oxidative stress on heart and blood vessels. Although NOX-dependent ROS production is implicated in pathogenesis, the relationship between HDACs and NOXs in CVDs remains to be elucidated. Here, we present an overview of the...

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PMID: 39378612
DOI: 10.1016/j.redox.2024.103379

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