Article
The AP-1 site is essential for the promoter activity of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme: Possible involvement of the ERK1/2-JunB pathway.
Biochemical and biophysical research communications - 19 Sept 2008
Cevik Muhammer Ozgur, Katsuyama Masato, Kanda Sayaka, Kaneko Tetsuo, Iwata Kazumi, Ibi Masakazu, Matsuno Kuniharu, Kakehi Tomoko, Cui Wenhao, Sasaki Mika, Yabe-Nishimura Chihiro
Abstract excerpt
NADPH oxidase is a major source of the superoxide produced in cardiovascular tissues. The expression of NOX1, a catalytic subunit of NADPH oxidase, is induced by various vasoactive factors, including angiotensin II, prostaglandin (PG) F(2alpha), and platelet-derived growth factor (PDGF). It was r...
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