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Article

Suppression of NADPH oxidase attenuates hypoxia-induced dysfunctions of endothelial progenitor cells.

Biochemical and biophysical research communications - 22 Jan 2017

Liu Bin, Ren Kai-Di, Peng Jing-Jie, Li Tao, Luo Xiu-Ju, Fan Chengming, Yang Jin-Fu, Peng Jun

Abstract excerpt

NADPH oxidases (NOX) - derived reactive oxygen species (ROS) contribute to oxidative injury in hypoxia-induced pulmonary arterial hypertension. This study aims to evaluate the status of NOX in endothelial progenitor cells (EPCs) under hypoxic condition and to determine whether NOX inhibitors could attenuate hypoxia-induced dysfunctions of EPCs. EPCs were isolated from peripheral blood of SD rats and subjected to...

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Source

Identifiers

PMID: 27913300
DOI: 10.1016/j.bbrc.2016.11.161

Genes

NOX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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