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Article

NADPH oxidase-derived reactive oxygen species in the regulation of endothelial phenotype.

Pharmacological reports : PR - 1 Jan 2000

Dworakowski Rafał, Alom-Ruiz Sara P, Shah Ajay M

Abstract excerpt

Endothelial dysfunction comprising impairment of endothelium-dependent vasodilator function and increased endothelial activation contributes to the pathophysiology of cardiovascular diseases such as atherosclerosis, diabetic vasculopathy, heart failure and hypertension. The changes in endothelial phenotype in these conditions occur in response to diverse stimuli including inflammatory cytokines, activation of...

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PMID: 18276982

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