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Article

Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast.

The EMBO journal - 31 Oct 2007

Sopko Richelle, Huang Dongqing, Smith Jeffrey C, Figeys Daniel, Andrews Brenda J

Abstract excerpt

Cyclin-dependent kinases (CDKs) trigger essential cell cycle processes including critical events in G1 phase that culminate in bud emergence, spindle pole body duplication, and DNA replication. Localized activation of the Rho-type GTPase Cdc42p is crucial for establishment of cell polarity during G1, but CDK targets that link the Cdc42p module with cell growth and cell cycle commitment have remained largely...

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Identifiers

PMID: 17853895
DOI: 10.1038/sj.emboj.7601847
PMCID: PMC2063489

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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