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Article

Functions and functional domains of the GTPase Cdc42p.

Molecular biology of the cell - 1 Jan 2000

Kozminski K G, Chen A J, Rodal A A, Drubin D G

Abstract excerpt

Cdc42p, a Rho family GTPase of the Ras superfamily, is a key regulator of cell polarity and morphogenesis in eukaryotes. Using 37 site-directed cdc42 mutants, we explored the functions and interactions of Cdc42p in the budding yeast Saccharomyces cerevisiae. Cytological and genetic analyses of these cdc42 mutants revealed novel and diverse phenotypes, showing that Cdc42p possesses at least two distinct essential...

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Identifiers

PMID: 10637312
DOI: 10.1091/mbc.11.1.339
PMCID: PMC14778

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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