Article
The shared role of the Rsr1 GTPase and Gic1/Gic2 in Cdc42 polarization.
Molecular biology of the cell - 1 Oct 2018
Kang Pil Jung, Miller Kristi E, Guegueniat Julia, Beven Laure, Park Hay-Oak
Abstract excerpt
The Cdc42 GTPase plays a central role in polarity development in many species. In budding yeast, Cdc42 is essential for polarized growth at the proper site and also for spontaneous cell polarization in the absence of spatial cues. Cdc42 polarization is critical for multiple events in the G1 phase prior to bud emergence, including bud-site assembly, polarization of the actin cytoskeleton, and septin filament...
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