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Article

Different domains of the essential GTPase Cdc42p required for growth and development of Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Jan 2001

Mösch H U, Köhler T, Braus G H

Abstract excerpt

In budding yeast, the Rho-type GTPase Cdc42p is essential for cell division and regulates pseudohyphal development and invasive growth. Here, we isolated novel Cdc42p mutant proteins with single-amino-acid substitutions that are sufficient to uncouple functions of Cdc42p essential for cell division from regulatory functions required for pseudohyphal development and invasive growth. In haploid cells, Cdc42p is...

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Identifiers

PMID: 11113198
DOI: 10.1128/MCB.21.1.235-248.2001
PMCID: PMC88797

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Source receipt: pubmed, retrieved 7 Sept 2026.

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