Article
GTPase-activating proteins for Cdc42.
Eukaryotic cell - 1 Jun 2002
Smith Gregory R, Givan Scott A, Cullen Paul, Sprague George F
Abstract excerpt
The Rho-type GTPase, Cdc42, has been implicated in a variety of functions in the yeast life cycle, including septin organization for cytokinesis, pheromone response, and haploid invasive growth. A group of proteins called GTPase-activating proteins (GAPs) catalyze the hydrolysis of GTP to GDP, thereby inactivating Cdc42. At the time this study began, there was one known GAP, Bem3, and one putative GAP, Rga1, for...
Topics
- Amino Acid Sequence
- GTPase-Activating Proteins
- Gene Deletion
- Genes, Fungal
- Genes, Reporter
- Haploidy
- Lac Operon
- Molecular Sequence Data
- Mutation
- Phenotype
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Sequence Homology, Amino Acid
- Signal Transduction
- cdc42 GTP-Binding Protein, Saccharomyces cerevisiae