Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation.

doi:10.1083/jcb.127.5.1381

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Article

Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation.

The Journal of cell biology - 1 Dec 1994

Kim Y J, Francisco L, Chen G C, Marcotte E, Chan C S

Abstract excerpt

The IPL2 gene is known to be required for normal polarized cell growth in the budding yeast Saccharomyces cerevisiae. We now show that IPL2 is identical to the previously identified BEM2 gene. bem2 mutants are defective in bud site selection at 26 degrees C and localized cell surface growth and organization of the actin cytoskeleton at 37 degrees C. BEM2 encodes a protein with a COOH-terminal domain homologous to...

Topics

Amino Acid Sequence
Base Sequence
Carrier Proteins
Cell Cycle Proteins
Cell Division
Cell Polarity
Chitin
Enzyme Activation
F-Box Proteins
Fungal Proteins
GTP Phosphohydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

GTP-Binding Proteins

GTPase-Activating Proteins

Genes, Fungal

Molecular Sequence Data

Monomeric GTP-Binding Proteins

Morphogenesis

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 7962097
DOI: 10.1083/jcb.127.5.1381
PMCID: PMC2120258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7962097-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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