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Candidate genes controlling pulmonary function in mice: transcript profiling and predicted protein structure

6 Sept 2007

Abstract excerpt

Impaired development and reduced lung capacity are risk factors of asthma and chronic obstructive pulmonary disease. Previously, our genomewide linkage analysis of C3H/HeJ (C3H) and JF1/Msf (JF1) mouse strains identified quantitative trait loci (QTLs) associated with the complex traits of dead space volume (Vd), total lung capacity (TLC), lung compliance (CL), and diffusing capacity for CO (D(CO)). We assessed...

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PMID: 17804602
DOI: 10.1152/physiolgenomics.00260.2006

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