Article
Fine mapping of the major bleomycin-induced pulmonary fibrosis susceptibility locus in mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2018
Bergeron Marie-Eve, Stefanov Anguel, Haston Christina K
Abstract excerpt
Susceptibility to fibrotic lung disease differs among people and among inbred strains of mice exposed to bleomycin where C57BL/6J mice are susceptible and C3H/HeJ mice are spared fibrotic disease. Genetic mapping studies completed in offspring derived from these inbred strains revealed the inheritance of C57BL/6J alleles at loci, including the major locus on chromosome 17, called Blmpf1 bleomycin-induced...
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