Article

A novel gene-by-environment quantitative trait locus on mouse chromosome 15 underlies susceptibility to acute ozone-induced lung injury

2021-05-20

Abstract excerpt

Respiratory toxicity caused by the common urban air pollutant ozone (O 3 ) varies considerably within the human population and across inbred mouse strains, suggestive of gene-environment interactions (GxE). Though previous studies genetic mapping studies using classical inbred strains have identified several and quantitative trait locus (QTL) and candidate genes underlying responses to O 3 exposure, precise mech...

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Literature Corpus work: ba33cc5e-6104-5fad-91f7-ac2bf243a761
DOI: 10.1101/2021.05.20.445039

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