Article
Genomewide linkage analysis identifies novel genetic Loci for lung function in mice.
American journal of respiratory and critical care medicine - 15 Apr 2005
Reinhard Claudia, Meyer Birgit, Fuchs Helmut, Stoeger Tobias, Eder Gunter, Rüschendorf Franz, Heyder Joachim, Nürnberg Peter, de Angelis Martin Hrabé, Schulz Holger
Abstract excerpt
RATIONALE: Pulmonary function, including lung volumes and compliance, may be genetically determined, but few genetic polymorphisms have been identified that control these traits. We used an experimental approach and performed the first whole genome scan for pulmonary function in mice. OBJECTIVES AND METHODS: To identify novel chromosomal regions contributing to lung function, quantitative trait locus linkage...
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