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Article

Biased clustered substitutions in the human genome: the footprints of male-driven biased gene conversion.

Genome research - 1 Oct 2007

Dreszer Timothy R, Wall Gregory D, Haussler David, Pollard Katherine S

Abstract excerpt

We examined fixed substitutions in the human lineage since divergence from the common ancestor with the chimpanzee, and determined what fraction are AT to GC (weak-to-strong). Substitutions that are densely clustered on the chromosomes show a remarkable excess of weak-to-strong "biased" substitutions. These unexpected biased clustered substitutions (UBCS) are common near the telomeres of all autosomes but not the...

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Identifiers

PMID: 17785536
DOI: 10.1101/gr.6395807
PMCID: PMC1987345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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