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Article

The impact of recombination on nucleotide substitutions in the human genome.

PLoS genetics - 9 May 2008

Duret Laurent, Arndt Peter F

Abstract excerpt

Unraveling the evolutionary forces responsible for variations of neutral substitution patterns among taxa or along genomes is a major issue for detecting selection within sequences. Mammalian genomes show large-scale regional variations of GC-content (the isochores), but the substitution processes at the origin of this structure are poorly understood. We analyzed the pattern of neutral substitutions in 1 Gb of...

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Identifiers

PMID: 18464896
DOI: 10.1371/journal.pgen.1000071
PMCID: PMC2346554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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