Article
A fine-scale recombination map of the human-chimpanzee ancestor reveals faster change in humans than in chimpanzees and a strong impact of GC-biased gene conversion.
Genome research - 1 Mar 2014
Munch Kasper, Mailund Thomas, Dutheil Julien Y, Schierup Mikkel Heide
Abstract excerpt
Recombination is a major determinant of adaptive and nonadaptive evolution. Understanding how the recombination landscape has evolved in humans is thus key to the interpretation of human genomic evolution. Comparison of fine-scale recombination maps of human and chimpanzee has revealed large changes at fine genomic scales and conservation over large scales. Here we demonstrate how a fine-scale recombination map...
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