Article
Apolipoprotein E phenotyping: a word of caution.
Annals of clinical biochemistry - 1 Nov 1991
Wenham P R, Sedky A, Spooner R J
Abstract excerpt
Using two different techniques, phenotyping and genotyping, we have studied allelic variation at amino acids 112 and 158 of the apolipoprotein E gene locus in 52 patients with insulin-dependent diabetes and in 58 non-diabetic controls. Phenotypes were determined by isoelectric focusing and immunoblotting of delipidated, neuraminidase-treated plasma. Genotypes were determined by using the polymerase chain reaction...
Topics
- Alleles
- Apolipoproteins E
- Diabetes Mellitus, Type 1
- Female
- Genotype
- Humans
- Male
- Phenotype
