Article
Estimation of the frequency of isoform-genotype discrepancies at the apolipoprotein E locus in heterozygotes for the isoforms.
Genetic epidemiology - 1 Jan 1992
Mailly F, Moll P, Kottke B A, Kamboh M I, Humphries S E, Ferrell R E
Abstract excerpt
Estimates of the impact of apolipoprotein E (apo E) alleles coding for the three common isoforms on plasma lipid levels assume genetic homogeneity among the genotype classes. To test this assumption, we have determined the apo E genotype at the two common polymorphic sites (amino acids 112 and 15...
Topics
- Adult
- Apolipoproteins E
- Base Sequence
- Cardiovascular Diseases
- Female
- Genotype
- Heterozygote
- Humans
- Isoelectric Focusing
- Male
- Middle Aged
- Molecular Sequence Data
- Oligonucleotide Probes
- Phenotype
- Polymerase Chain Reaction
- White People