Article
Disparity between apolipoprotein E phenotypes and genotypes (as determined by polymerase chain reaction and oligonucleotide probes) in patients with non-insulin-dependent diabetes mellitus.
Clinica chimica acta; international journal of clinical chemistry - 31 Jan 1991
Snowden C, Houlston R S, Arif M H, Laker M F, Humphries S E, Alberti K G
Abstract excerpt
Apolipoprotein (apo) E phenotype and genotype frequencies, due to allelic variation at amino acids 112 and 158, have been investigated in 95 Caucasian non-insulin dependent diabetic patients (NIDDM). Phenotypes were determined by one-dimensional isoelectric focussing (IEF). In this sample, the fr...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Apolipoproteins E
- Base Sequence
- Diabetes Mellitus, Type 2
- Female
- Gene Frequency
- Genetic Variation
- Genotype
- Humans
- Isoelectric Focusing
- Male
- Middle Aged
- Molecular Sequence Data