Article
Apolipoprotein E phenotypes and plasma lipids in diabetic children and adolescents.
European journal of pediatrics - 1 Jul 1993
Salo M K, Rantanen R, Huupponen T, Lehtimäki T, Jokela H
Abstract excerpt
Apolipoprotein E (apoE) polymorphism is a genetic determinant of serum lipoprotein levels and coronary heart disease risk. ApoE appears in three major isoforms E2, E3 and E4, coded by corresponding alleles epsilon 2, epsilon 3 and epsilon 4. These give six different phenotypes. Patients with insulin dependent diabetes (IDDM) have been reported to have increased incidence of E2/2 homozygosity. We studied the...
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