Frequency of phenotype-genotype discrepancies at the apolipoprotein E locus in a large population study.

Article

Frequency of phenotype-genotype discrepancies at the apolipoprotein E locus in a large population study.

Clinical chemistry - 1 Nov 1996

Lahoz C, Osgood D, Wilson P W, Schaefer E J, Ordovas J M

Abstract excerpt

Apolipoprotein E (apoE) genotypes were determined in a random subset of 1041 subjects enrolled in the Framingham Offspring Study by using DNA amplification followed by restriction isotyping. The results were compared with the apoE phenotypes previously assessed by isoelectric focusing. Discrepanc...

Topics

Adult
Aged
Apolipoproteins E
Cholesterol
Cholesterol, HDL
Cholesterol, LDL
DNA Primers
Female
Genotype
Humans
Isoelectric Focusing
Male
Middle Aged
Phenotype
Triglycerides

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