Article
Discrepancies between apolipoprotein E phenotyping and genotyping in the elderly.
Clinical chemistry and laboratory medicine - 1 May 2001
Dupuy A M, Badiou S, Ritchie K, Mas E, Descomps B, Cristol J P, Touchon J
Abstract excerpt
We estimated the frequencies of phenotype (isoelectric focusing; IEF) vs. genotype (PCR/Hhal) discordance in a sample of an aged population (> 65 years). Both phenotype and genotype techniques have been used in the study of apolipoprotein E (apoE) polymorphism in 125 elderly subjects. The discordance between phenotype and genotype was unresolved in 11 (8.8%) of the 125 unrelated subjects studied. We observed a...
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