Genotyping compared with protein phenotyping of the common apolipoprotein E polymorphism.

doi:10.1016/0009-8981(94)90179-1

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Article

Genotyping compared with protein phenotyping of the common apolipoprotein E polymorphism.

Clinica chimica acta; international journal of clinical chemistry - 31 Jan 1994

Hansen P S, Gerdes L U, Klausen I C, Gregersen N, Faergeman O

Abstract excerpt

Apolipoprotein E (apo E) genotypes have been determined in 460 Danish men, with the use of the polymerase chain reaction (PCR) to amplify a 244 base pair fragment spanning the first-base polymorphic sites in the codons of amino acids 112 and 158 followed by restriction endonuclease cleavage. The...

Topics

Adult
Amino Acids
Apolipoproteins E
Denmark
Epidemiologic Methods
Genotype
Humans
Isoelectric Focusing
Male
Phenotype
Polymerase Chain Reaction
Polymorphism, Genetic

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