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Article

The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation.

Molecular biology of the cell - 1 Nov 2007

Pathak Narendra, Obara Tomoko, Mangos Steve, Liu Yan, Drummond Iain A

Abstract excerpt

Cilia and basal bodies are essential organelles for a broad spectrum of functions, including the development of left-right asymmetry, kidney function, cerebrospinal fluid transport, generation of photoreceptor outer segments, and hedgehog signaling. Zebrafish fleer (flr) mutants exhibit kidney cysts, randomized left-right asymmetry, hydrocephalus, and rod outer segment defects, suggesting a pleiotropic defect in...

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Identifiers

PMID: 17761526
DOI: 10.1091/mbc.e07-06-0537
PMCID: PMC2043541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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