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Article

Functional genomics of the cilium, a sensory organelle.

Current biology : CB - 24 May 2005

Blacque Oliver E, Perens Elliot A, Boroevich Keith A, Inglis Peter N, Li Chunmei, Warner Adam, Khattra Jaswinder, Holt Rob A, Ou Guangshuo, Mah Allan K, McKay Sheldon J, Huang Peter, Swoboda Peter, Jones Steve J M, Marra Marco A, Baillie David L, Moerman Donald G, Shaham Shai, Leroux Michel R

Abstract excerpt

Cilia and flagella play important roles in many physiological processes, including cell and fluid movement, sensory perception, and development. The biogenesis and maintenance of cilia depend on intraflagellar transport (IFT), a motility process that operates bidirectionally along the ciliary axoneme. Disruption in IFT and cilia function causes several human disorders, including polycystic kidneys, retinal...

Topics

Animals
Base Sequence
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Cilia
Computational Biology
Gene Expression Profiling
Genomics
Green Fluorescent Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neurons

Protein Transport

Sequence Analysis, DNA

Transcription Factors

Source

Identifiers

PMID: 15916950
DOI: 10.1016/j.cub.2005.04.059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-15916950-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Functional genomics of the cilium, a sensory organelle.PMID 15916950Read ↗

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