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Article

Caenorhabditis elegans DYF-2, an orthologue of human WDR19, is a component of the intraflagellar transport machinery in sensory cilia.

Molecular biology of the cell - 1 Nov 2006

Efimenko Evgeni, Blacque Oliver E, Ou Guangshuo, Haycraft Courtney J, Yoder Bradley K, Scholey Jonathan M, Leroux Michel R, Swoboda Peter

Abstract excerpt

The intraflagellar transport (IFT) machinery required to build functional cilia consists of a multisubunit complex whose molecular composition, organization, and function are poorly understood. Here, we describe a novel tryptophan-aspartic acid (WD) repeat (WDR) containing IFT protein from Caenorhabditis elegans, DYF-2, that plays a critical role in maintaining the structural and functional integrity of the IFT...

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Identifiers

PMID: 16957054
DOI: 10.1091/mbc.e06-04-0260
PMCID: PMC1635379

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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