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Article

Estrogen receptor genotypes, menopausal status, and the lipid effects of tamoxifen.

Clinical pharmacology and therapeutics - 1 May 2008

Ntukidem N I, Nguyen A T, Stearns V, Rehman M, Schott A, Skaar T, Jin Y, Blanche P, Li L, Lemler S, Hayden J, Krauss R M, Desta Z, Flockhart D A, Hayes D F

Abstract excerpt

Tamoxifen induces important changes in serum lipid profiles in some women; however, little information is available to predict which women will experience improved lipid profiles during tamoxifen therapy. As part of a multicenter prospective observational trial in 176 breast cancer patients, we tested the hypothesis that tamoxifen-induced lipid changes were associated with genetic variants in candidate target...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17713466
DOI: 10.1038/sj.clpt.6100343
PMCID: PMC2782693

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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