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Article

Exonic, but not intronic polymorphisms of ESR1 gene might influence the hypolipemic effect of raloxifene.

The Journal of steroid biochemistry and molecular biology - 1 Apr 2007

Zavratnik Andrej, Prezelj Janez, Kocijancic Andreja, Marc Janja

Abstract excerpt

UNLABELLED: Studies have shown that selective modulator of estrogen receptor raloxifene, exerts hypolipemic properties at least partially through estrogen receptor alpha activation. To test the hypothesis that polymorphisms of estrogen receptor alpha are associated with the influence of 6 months raloxifene treatment on serum lipids, two intronic (PvuII and XbaI), and one exonic polymorphism (P325P) were analyzed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17350824
DOI: 10.1016/j.jsbmb.2006.10.009

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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