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Article

Lack of association between oestrogen receptor polymorphisms and change in bone mineral density with tamoxifen therapy.

British journal of cancer - 19 Jan 2010

Henry N L, Nguyen A, Azzouz F, Li L, Robarge J, Philips S, Cao D, Skaar T C, Rae J M, Storniolo A M, Flockhart D A, Hayes D F, Stearns V

Abstract excerpt

BACKGROUND: Tamoxifen, a selective oestrogen receptor (ER) modulator, increases bone mineral density (BMD) in postmenopausal women and decreases BMD in premenopausal women. We hypothesised that inherited variants in candidate genes involved in oestrogen signalling and tamoxifen metabolism might b...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19953095
DOI: 10.1038/sj.bjc.6605460
PMCID: PMC2816645

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19953095-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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