Article
Tamoxifen therapy in breast cancer: do apolipoprotein E genotype and menopausal state affect plasma lipid changes induced by the drug?
The International journal of biological markers - 17 Dec 2013
Gaibar María, Fernández Gerónimo, Romero-Lorca Alicia, Novillo Apolonia, Tejerina Armando, Bandrés Fernando, Fernández-Santander Ana
Abstract excerpt
OBJECTIVE: This study examines the lipid profile change produced in response to tamoxifen (TAM) treatment, and its possible relationship with both apolipoprotein E genotype and menopausal state in patients with breast cancer. METHODS: Blood samples were collected from 86 Spanish women with breast cancer before initiating TAM treatment and in the following 6, 12 and 18 months of treatment. Plasma lipid levels...
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