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Article

Estrogen receptor genotypes, menopausal status, and the effects of tamoxifen on lipid levels: revised and updated results.

Clinical pharmacology and therapeutics - 1 Nov 2010

Hayes D F, Skaar T C, Rae J M, Henry N L, Nguyen A T, Stearns V, Li L, Philips S, Desta Z, Flockhart D A

Abstract excerpt

We previously reported that the ESR1 XbaI genotypes were associated with baseline and tamoxifen-induced serum lipid profiles. The analysis in that study was carried out by PCR followed by restriction-enzyme digestion. After reanalysis using more robust TaqMan assays, the findings related to ~10% of the genotypes for the ESR1 XbaI single-nucleotide polymorphism (SNP) were revised. For the other genotypes (i.e.,...

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Source

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Identifiers

PMID: 20827267
DOI: 10.1038/clpt.2010.143
PMCID: PMC4077673

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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