Are polymorphisms in oestrogen receptors genes associated with lipid levels in response to hormone therapy?

doi:10.3109/09513590.2011.650767

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Article

Are polymorphisms in oestrogen receptors genes associated with lipid levels in response to hormone therapy?

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Aug 2012

Smiderle Lisiane, Mattevi Vanessa Suñé, Giovenardi Márcia, Wender Maria Celeste Osório, Hutz Mara Helena, Almeida Silvana

Abstract excerpt

BACKGROUND: Polymorphisms in the oestrogen receptor 1 (ESR1) and oestrogen receptor 2 (ESR2) genes are associated with intermediate or endpoint markers of cardiovascular disease and with the efficacy of postmenopausal hormone therapy (HT). Contradictory findings have been described in the past and the role of these genetics variants remains unclear. METHODS: A cross-sectional study was carried out with 266...

Topics

Adult
Aged
Biomarkers, Pharmacological
Brazil
Cardiovascular Diseases
Cholesterol
Cholesterol, LDL
Cross-Sectional Studies
Estrogen Receptor alpha
Estrogen Receptor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Estrogen Replacement Therapy

Estrogens

Female

Genetic Association Studies

Humans

Hyperlipidemias

Middle Aged

Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 22324545
DOI: 10.3109/09513590.2011.650767

Genes

ESR2
ESR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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