Article
ESR1 and APOE gene polymorphisms, serum lipids, and hormonal replacement therapy.
Maturitas - 20 May 2006
Almeida Silvana, Fiegenbaum Marilu, de Andrade Fabiana M, Osório-Wender Maria C, Hutz Mara H
Abstract excerpt
OBJECTIVES: The risks and benefits of hormone replacement therapy (HRT) are, at least in part, mediated by the metabolic individuality of women. Therefore, we investigated the association between polymorphisms at the estrogen receptor 1 gene (ESR1) and at the apolipoprotein E gene (APOE) with lipid and lipoprotein levels in order to verify whether these concentrations are modulated by these gene variants in women...
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