Article
Apolipoprotein E genotype and response of lipid levels to postmenopausal estrogen use.
Atherosclerosis - 1 Mar 2002
von Muhlen Denise, Barrett-Connor Elizabeth, Kritz-Silverstein Donna
Abstract excerpt
The allelic variation of Apolipoprotein E (ApoE) influences serum lipid levels. Postmenopausal estrogen replacement therapy (ERT) has favorable effects on the serum lipid profile. We examined the effect of ApoE genotype on lipid response to ERT in 692 community-dwelling women aged 60 and older. ApoE genotypes were categorized into three groups: ApoE 2 (E2/E2+E2/E3, n=94), ApoE 3 (E3/E3, n=430), and ApoE 4...
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