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Article

ESR1 polymorphisms and statin therapy: a sex-specific approach.

The pharmacogenomics journal - 1 Nov 2016

Smiderle L, Fiegenbaum M, Hutz M H, Van Der Sand C R, Van Der Sand L C, Ferreira M E W, Pires R C, Almeida S

Abstract excerpt

Lipid-lowering therapy has shown a high degree of variability in clinical response and there is evidence that the variability in drug response between individuals is due to genetic factors. Thirteen single nucleotide polymorphisms (SNPs) within the ESR1 gene were evaluated with basal lipid and lipoprotein levels, as well as response to lipid-lowering therapy, in 495 hypercholesterolemic individuals of European...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26302681
DOI: 10.1038/tpj.2015.60

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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