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Article

Expansion and function of Foxp3-expressing T regulatory cells during tuberculosis.

The Journal of experimental medicine - 3 Sept 2007

Scott-Browne James P, Shafiani Shahin, Tucker-Heard Glady's, Ishida-Tsubota Kumiko, Fontenot Jason D, Rudensky Alexander Y, Bevan Michael J, Urdahl Kevin B

Abstract excerpt

Mycobacterium tuberculosis (Mtb) frequently establishes persistent infections that may be facilitated by mechanisms that dampen immunity. T regulatory (T reg) cells, a subset of CD4(+) T cells that are essential for preventing autoimmunity, can also suppress antimicrobial immune responses. We use Foxp3-GFP mice to track the activity of T reg cells after aerosol infection with Mtb. We report that during...

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Identifiers

PMID: 17709423
DOI: 10.1084/jem.20062105
PMCID: PMC2118702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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