Article
Identification and characterization of T reg-like cells in zebrafish.
The Journal of experimental medicine - 4 Dec 2017
Kasheta Melissa, Painter Corrie A, Moore Finola E, Lobbardi Riadh, Bryll Alysia, Freiman Eli, Stachura David, Rogers Arlin B, Houvras Yariv, Langenau David M, Ceol Craig J
Abstract excerpt
Regulatory T (T reg) cells are a specialized sublineage of T lymphocytes that suppress autoreactive T cells. Functional studies of T reg cells in vitro have defined multiple suppression mechanisms, and studies of T reg-deficient humans and mice have made clear the important role that these cells play in preventing autoimmunity. However, many questions remain about how T reg cells act in vivo. Specifically, it is...
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