Article
Functional dynamics of Foxp3⁺ regulatory T cells in mice and humans.
Immunological reviews - 1 May 2014
Bin Dhuban Khalid, Kornete Mara, S Mason Edward, Piccirillo Ciriaco A
Abstract excerpt
Forkhead box protein 3 (Foxp3)(+) regulatory T (Treg) cells are critical mediators for the establishment of self-tolerance and immune homeostasis and for the control of pathology in various inflammatory responses. While Foxp3(+) Treg cells often control immune responses in secondary lymphoid tissues, they must also traffic to and persist within non-lymphoid tissues, where they integrate various environmental cues...
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