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Article

Foxp4 Is Dispensable for T Cell Development, but Required for Robust Recall Responses

13 Aug 2012

Abstract excerpt

Transcription factors regulate T cell fates at every stage of development and differentiation. Members of the Foxp family of forkhead transcription factors are essential for normal T lineage development; Foxp3 is required for T regulatory cell generation and function, and Foxp1 is necessary for generation and maintenance of naïve T cells. Foxp4, an additional member of the Foxp family, is highly homologous to...

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PMID: 22912696
DOI: 10.1371/journal.pone.0042273

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