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Regulation of Immunity to Tuberculosis

23 Dec 2016

Abstract excerpt

Immunity against Mycobacterium tuberculosis requires a balance between adaptive immune responses to constrain bacterial replication and the prevention of potentially damaging immune activation. Regulatory T (Treg) cells express the transcription factor Foxp3+ and constitute an essential counterbalance of inflammatory Th1 responses and are required to maintain immune homeostasis. The first reports describing the...

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PMID: 28087948
DOI: 10.1128/microbiolspec.tbtb2-0006-2016

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