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Cutting Edge: Regulatory T Cells Prevent Efficient Clearance of Mycobacterium tuberculosis

1 Mar 2007

Abstract excerpt

Mycobacterium tuberculosis remains one of the top microbial killers of humans causing approximately 2 million deaths annually. More than 90% of the 2 billion individuals infected never develop active disease, indicating that the immune system is able to generate mechanisms that control infection. However, the immune response generally fails to achieve sterile clearance of bacilli. Using adoptive cell transfer...

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PMID: 17312107
DOI: 10.4049/jimmunol.178.5.2661

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