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Article

[Prevalence of FLT3 internal tandem duplication in adult acute myelogenous leukemia].

The Korean journal of laboratory medicine - 1 Aug 2007

Lee Jeong Nyeo, Kim Hye Ran, Shin Jeong Hwan, Joo Young Don

Abstract excerpt

BACKGROUND: fms-like tyrosine kinase (FLT3), a member of the class III receptor tyrosine kinases, regulates the proliferation and differentiation of hematopoietic stem cells. An internal tandem duplication of the FLT3 gene (FLT3/ITD) has been reported in acute myelogenous leukemia (AML) and may be associated with a poor prognosis. In this study we determined the prevalence and prognostic significance of FLT3/ITD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18094582
DOI: 10.3343/kjlm.2007.27.4.237

Genes

FLT3

Provenance

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