Article
[Flt-3/ITD mutation in pediatric leukemia and its clinical significance].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Jan 2007
Wang Jie, Wang Tong, Li Shu, Lin Li, Gang Yan
Abstract excerpt
BACKGROUND & OBJECTIVE: Flt-3 internal tandem duplication (Flt-3/ITD) in transmembrane region is the most frequently identified mutation in Flt-3 gene, which is the most frequently happened in acute myeloid leukemia (AML) and correlated to prognosis. This study was to explore the correlation of Flt-3/ITD mutation to the occurrence of pediatric leukemia, and analyze its clinical significance. METHODS: Flt-3/ITD...
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