Article
[Analysis of ITD characteristics in acute myeloid leukemia patients with FLT3-ITD positive].
Zhongguo shi yan xue ye xue za zhi - 1 Oct 2011
Ma Liang, Feng Dai-Rong, Zhong Ming-Hua, Wang Li-Wei, Cai Ying, Ma Yi-Gai, Huang Shang-Zhi
Abstract excerpt
The aim of this study was to analyze the FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) allelic ratios (AR), number of ITD, ITD length and positions of ITD insertions in de novo acute myeloid leukemia (AML) patients with FLT3-ITD positive, and the relationship between mutant level and therapeutic efficacy. Genomic DNA was amplified by PCR, capillary electrophoresis was used to detect the ITD...
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