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Article

Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain.

Nucleic acids research - 1 Jan 2007

Noeske Jonas, Schwalbe Harald, Wöhnert Jens

Abstract excerpt

Divalent cations are important in the folding and stabilization of complex RNA structures. The adenine-sensing riboswitch controls the expression of mRNAs for proteins involved in purine metabolism by directly sensing intracellular adenine levels. Adenine binds with high affinity and specificity to the ligand binding or aptamer domain of the adenine-sensing riboswitch. The X-ray structure of this domain in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17686787
DOI: 10.1093/nar/gkm565
PMCID: PMC1976443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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