Nuclear import of c-Jun is mediated by multiple transport receptors.

Abstract excerpt

c-Jun and c-Fos are major components of the transcriptional complex AP-1. Here, we investigate the nuclear import pathway(s) of the transcription factor c-Jun. c-Jun bound specifically to the nuclear import receptors importin beta, transportin, importin 5, importin 7, importin 9, and importin 13. In digitonin-permeabilized cells, importin beta, transportin, importin 7, and importin 9 promoted efficient import of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Karyopherins
• Share to Leucine Zippers
• Share to Nuclear Localization Signals