Article
The Drosophila melanogaster importin alpha3 locus encodes an essential gene required for the development of both larval and adult tissues.
Genetics - 1 Dec 2003
Mason D Adam, Máthé Endre, Fleming Robert J, Goldfarb David S
Abstract excerpt
The nuclear transport of classical nuclear localization signal (cNLS)-containing proteins is mediated by the cNLS receptor importin alpha. The conventional importin alpha gene family in metazoan animals is composed of three clades that are conserved between flies and mammals and are referred to here as alpha1, alpha2, and alpha3. In contrast, plants and fungi contain only alpha1 genes. In this study we report...
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